Bone Marrow Perls Stain
Bone Marrow is the spongy tissue inside of the Bones. It produces white blood cells, Red blood cells, and Platelets. Perls Stain is helpful to examine the presence of ferric iron in the Bone marrow tissues to check the Iron Deficiency in diagnosing Anemia and Leukemia.
Bone Marrow –Perls Stain:
Why Bone Marrow – Perls Stain test?
CLINICAL INFORMATION :
Perls Stain is a cheap and relatively simple test that can be used as a routine test in all bone marrow aspirates to provide provisional diagnosis like in cases of chronic anemias, fever of unknown origin, etc. The gold standard method for the diagnosis of iron deficiency is assessed by Perls’ stain test. Microscopic examination of Perls’ Prussian blue stained bone marrow aspirate smears is considered the gold standard for the assessment of the marrow iron store in the body. This test is also useful in the diagnosis of sideroblastic anemia, thalassemia, etc. Other tests for iron deficiency are blood tests including serum iron, TIBC – Total Iron Binding Capacity, and serum ferritin.
General instructions:
Sample Requirement: Specimen –Fluid sample collected from the bone marrow. Test Preparation: As suggested by the Doctor.
NOTE - Sample for specimen collections may vary based on the patient’s condition/cases according to the patient’s presenting complaints/signs or symptoms:
SPECIMEN REQUIREMENT (Special or Rare Cases) - As instructed and guided by Physician / Clinician / Pathologist / as per Laboratory’s requirements, according to procedures and protocols.
