ANCA – MPO –pANCA:
Why ANCA – MPO –pANCA test?
CLINICAL INFORMATION :
ANCA – MPO –pANCA is Antineutrophil Cytoplasmic Antibodies produced by the immune system. ANCA reacts with enzymes in the cytoplasmic granules of human neutrophils such as protease-3, myeloperoxidase (MPO), elastase, and cathepsin G. Elevated levels of MPO are associated with vascular diseases, lupus, and other inflammatory conditions. Perinuclear anti-neutrophil cytoplasmic antibodies are those that stain the materials around the nucleus of a neutrophil. The most common pANCA target is myeloperoxidase (MPO), a neutrophil granule protein whose primary role is the normal metabolic process of generating oxygen radicals. In conditions like vasculitis, the target is usually MPO. This test helps to detect and diagnose certain types of auto-J), microscopic polyangitis, and eosinophilic granulomatosis with polyangitis (Churg Strauss syndrome).
General instructions:
Sample Requirement: Specimen - Blood sample taken from the vein. Test Preparation: None.
NOTE - Sample for specimen collections may vary based on the patient’s condition/cases according to the patient’s presenting complaints/signs or symptoms:
SPECIMEN REQUIREMENT (Special or Rare Cases) - As instructed and guided by Physician / Clinician / Pathologist / as per Laboratory’s requirements, according to procedures and protocols.
This Multi-Specialty Clinical Referral Laboratory RTDIAGNOSTICS provides precise and accurate tests with an extensive range of testing services to the medical centers to help in the diagnosis and identification of pathology in the test specimens for infectious diseases and also to evaluate the function of organ systems of the patient. It prevents further complications and helps to stabilize and restore health to near normalcy at the earliest without delay.
