ANCA (IFA Method)
ANCA- Antineutrophil Cytoplasmic Antibodies are Autoantibodies created by the abnormal Immune System. Sometimes Antibodies are triggered against self-antigens of the body, such as neutrophils PROTEIN(Kind of white blood cells). ANCA IFA (Indirect Fluorescent Antibody) method is a primary test to examine antibodies in the blood sample to diagnose autoimmune disorders.
ANCA – IFA Method:
Why ANCA - IFA test?
CLINICAL INFORMATION :
ANCA – IFA test method detects anti-neutrophil cytoplasmic antibodies (ANCAs) in serum. These auto-antibodies are mainly IgG against an antigen in the cytoplasm of neutrophil granulocytes (and monocytes). This ANCA test and/or test for MPO and PR3 are ordered with signs and symptoms of systemic autoimmune vasculitis and inflammatory bowel disease. The clinical manifestations of systemic auto-immune vasculitis include Eyes- red, itchy eyes, pink eye (conjunctivitis), blurry vision, or/and loss of vision. Ears – hearing loss, Nose – runny nose, and upper respiratory symptoms, skin – rashes and/or granulomas, Lungs – cough and/or difficulty breathing, Kidneys – proteinuria. The clinical manifestations of inflammatory bowel disease include abdominal pain and cramps, diarrhea, rectal bleeding, fever, fatigue, and some symptoms associated with joints, skin, bone, and other organ-related symptoms. Usually, this test is performed along with anti-saccharomyces cerevisiae antibodies (ASCA). This test is a differential diagnosis for ulcerative colitis and Crohn’s disease.
General instructions:
Sample Requirement: Specimen - Blood sample taken from the vein. Test Preparation: None.
NOTE - Sample for specimen collections may vary based on the patient’s condition/cases according to the patient’s presenting complaints/signs or symptoms:
SPECIMEN REQUIREMENT (Special or Rare Cases) - As instructed and guided by Physician / Clinician / Pathologist / as per Laboratory’s requirements, according to procedures and protocols.
This Multi-Specialty Clinical Referral Laboratory RTDIAGNOSTICS provides precise and accurate tests with an extensive range of testing services to the medical centers to help in the diagnosis and identification of pathology in the test specimens for infectious diseases and also to evaluate the function of organ systems of the patient. It prevents further complications and helps to stabilize and restore health to near normalcy at the earliest without delay.
