ABSOLUTE GRANULOCYTE COUNT:
CLINICAL INFORMATION :
Neutrophils, eosinophils, and basophils are three types of granulocytes. Granulocyte count in a blood test measures three subtypes of granulocyte cells in a complete blood count. Granulocyte count is WBCs that have small granules or particles that help the immune system fight off a viral and bacterial infection. As an immune response, these granulocytes migrate to the site of infection and release a number of effector molecules such as histamines, cytokines, chemokinesis, enzymes, and growth factors.
Excessive granulocytes in the blood are known as granulocytosis. It occurs in conditions such as sepsis, kidney failure, rheumatoid arthritis, inflammatory bowel disease, emotional stress, burns, heart attack, autoimmune disease, blood cancers, chronic myelogenous leukemia, and certain medications such as corticosteroids. (CML), chemotherapy, bone marrow transplant, radiation therapy, splenectomy, and other bone disorders. Symptoms include frequent infections, abnormal bleeding, and fatigue, loss of appetite, pale skin, and night sweats. Absence or low granulocytes are called agranulocytosis or granulocytopenia. Some causes of agranulocytosis are bone marrow disease, spina bifida (myelodysplasia), chemotherapy and bone marrow transplant, etc. granulocytopenia can be caused due by congenital or acquired production of granulocyte precursors or it may be a consequence of the destruction of mature granulocytes (most commonly by immune mechanism). Symptoms include sudden fever, chills, sore throat, weakness, sore mouth and gums, ulcers in the mouth, bleeding gums, etc. Other associated tests include flow cytometry, antibody blood test, bone marrow aspirate, bone marrow biopsy, cytogenic and molecular testing, etc.
General instructions:
Sample Requirement: Specimen - Blood sample drawn from the vein/fingertip prick for capillary blood. Test Preparation: Get suggestions from your doctor.
NOTE - Sample for specimen collections may vary based on the patient’s condition/cases according to the patient’s presentingcomplaints / signs or symptoms:
SPECIMEN REQUIREMENT (Special or Rare Cases) - As instructed and guided by Physician / Clinician / Pathologist / as per Laboratory’s requirements, according to procedures and protocols.
This Multi-Specialty Clinical Referral Laboratory “RTDIAGNOSTICS” provides precise and accurate tests with an extensive range of testing services to the medical centers to help in the diagnosis and identification of pathology in the test specimens for infectious diseases and also to evaluate the function of organ systems of the patient. It prevents further complications and helps to stabilize and restore health to near normalcy at the earliest without delay.
