A₁- ANTITRYPSIN (A1AT):
Alpha₁- Antitrypsin is a protein substance that prevents the lungs from the destructive Enzymes. This test is helpful for diagnosing lung disorders like emphysema and also monitors the deficiency of A₁ Antitrypsin. This test is also known as A₁AT and AAT.
CLINICAL INFORMATION :
Alpha-1 antitrypsin (A1AT) is a circulating liver derived serine protease inhibitor (The main function is to balance the action of a neutrophil-protease enzyme in the lung i.e. neutrophil elastase enzyme produced by the neutrophils in the presence of inflammation, infection, or smoking) and it protects the lungs from damage and diseases like emphysema and COPD. High levels of these enzymes are found to stimulate tumor cell proliferation and invasions in different cancers. Deficiency of alpha-1 antitrypsin can cause various medical complications of the lungs, liver, and skin (Panniculitis - inflammation of fatty tissue under the skin), including COPD, emphysema, chronic bronchitis, and cirrhosis of the liver. Symptoms of alpha-1 antitrypsin are feeling tired, faster heartbeat when standing (postural hypertension), weight loss, yellow urine, yellowish eyes and/or skin, swollen legs or belly, coughing up blood etc. Other associated tests include bronchoscopy (for biopsy from lungs), colorimetric methods, spectroscopic methods, kit methods, etc.
General instructions:
Sample Requirement: Specimen - Blood sample drawn from the vein, Test Preparation: None.
NOTE - Sample for specimen collections may vary based on the patient’s condition/cases according to the patient’s presentingcomplaints / signs or symptoms:
SPECIMEN REQUIREMENT (Special or Rare Cases) - As instructed and guided by Physician / Clinician / Pathologist / as per Laboratory’s requirements, according to procedures and protocols.
This Multi-Specialty Clinical Referral Laboratory “RTDIAGNOSTICS” provides precise and accurate tests with an extensive range of testing services to the medical centers to help in the diagnosis and identification of pathology in the test specimens for infectious diseases and also to evaluate the function of organ systems of the patient. It prevents further complications and helps to stabilize and restore health to near normalcy at the earliest without delay.
